Voxelotor (By mouth)
Treats sickle cell disease.
OxbrytaThere may be other brand names for this medicine.
When This Medicine Should Not Be Used:This medicine is not right for everyone. Do not use it if you had an allergic reaction to voxelotor.
How to Use This Medicine:
- Your doctor will tell you how much medicine to use. Do not use more than directed.
- Swallow the tablet whole. Do not crush, break, or chew it.
- Your doctor may want you to take hydroxyurea while taking this medicine.
- Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
- Missed dose: If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Some medicines can affect how voxelotor works. Tell your doctor if you are using efavirenz, fluconazole, ketoconazole, midazolam, or rifampin.
Warnings While Using This Medicine:
- Tell your doctor if you are pregnant or if you have liver disease. Tell your doctor if you are receiving blood transfusions.
- Do not breastfeed during treatment and for at least 2 weeks after the last dose.
- Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
- Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Chest pain, trouble breathing
- Fever, chills, cough sore throat, body aches
- Swelling of the face
- Unusual bleeding or bruising
If you notice these less serious side effects, talk with your doctor:
- Diarrhea, nausea, stomach pain
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
Last Updated: 3/19/2020
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