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Iobenguane I 123 (By injection)

Iobenguane I 123 (eye-oh-BEN-gwane I 123)

Used to help view and measure tumors, heart problems, and other problems. Given before a medical test or procedure.

Brand Name(s):


There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. You should not receive it if you had an allergic reaction to iobenguane.

How to Use This Medicine:


  • Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
  • A nurse or other health provider will give you this medicine.
  • Drink extra fluids before and after you are given this medicine, so you will urinate often. You should urinate as much as possible for the first 48 hours after you were given this medicine. This will help protect your bladder from the radiation exposure.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Some medicines can affect how this medicine works or change the results of your test. Tell your doctor if you use any of the following:
    • Blood pressure medicine, such as labetalol, reserpine
    • Cocaine
    • Cold or allergy medicine, such as ephedrine, phenylephrine, pseudoephedrine
    • Medicine for depression, such as amitriptyline, citalopram, fluoxetine, imipramine, nortriptyline, sertraline

Warnings While Using This Medicine:

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, high blood pressure, Parkinson disease, or thyroid problems. Tell your doctor if you had an allergic reaction to iodine or anything that contains iodine.
  • You will be exposed to radiation when you are given this medicine. Talk with your doctor if you have concerns about this.
  • This medicine contains benzyl alcohol, which may cause serious reactions in premature or low-birth-weight infants.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Severe bleeding, pain, itching, burning, bruising, or swelling where the needle is placed

If you notice these less serious side effects, talk with your doctor:

  • Dizziness
  • Headache
  • Mild reaction where the needle is placed
  • Mild skin rash or itching
  • Warmth or redness in your face, neck, arms, or upper chest

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 5/1/2020

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