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Miconazole/zinc oxide/white petrolatum (On the skin)

Miconazole Nitrate (mye-KON-a-zole NYE-trate), Petrolatum, White (pet-roe-LAY-tum, white), Zinc Oxide (zink OX-ide)

Treats diaper rash caused by a yeast infection (candida or candidiasis). This is an antifungal medicine.

Brand Name(s):


There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. Do not give it if your child had an allergic reaction to miconazole nitrate, white petrolatum, or zinc oxide.

How to Use This Medicine:


  • This medicine is for use only on your child's skin. Do not get any of it into your child's eyes, nose, mouth, or vagina. Rinse it off right away if it does get on these areas.
  • Wash your hands with soap and water before and after you use this medicine.
  • Change wet and soiled diapers right away. Clean the diaper area with lukewarm water and pat dry with a soft towel.
  • Apply a thin layer of this medicine on your child's diaper area at each diaper change. Do not rub into your child's skin.
  • Keep using this medicine for the full 7 days, even if you do not see an improvement after the first few doses. Your child's infection may not clear up if you stop the medicine too soon.
  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
  • Missed dose: Apply a dose as soon as you can. If it is almost time for your next dose, wait until then and apply a regular dose. Do not apply extra medicine to make up for a missed dose.
  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Do not put cosmetics or skin care products on the treated skin.

Warnings While Using This Medicine:

  • Tell your doctor if you are pregnant or breastfeeding.
  • Do not use this medicine to treat a skin problem your doctor has not examined.
  • Do not use this medicine to prevent diaper rash.
  • Each antifungal medicine is made to treat a certain kind of infection. Use only the medicine your doctor has prescribed. You should not use an over-the-counter product in place of what your doctor has told you to use.
  • If the rash gets worse or does not get better after 7 days, call your doctor right away.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Severe skin irritation or rash at the application site

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 5/1/2020

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