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Botulism immune globulin (By injection)

Botulism Immune Globulin (BOT-ue-lizm i-MUNE GLOB-ue-lin)

Treats botulism in infants younger than 1 year.

Brand Name(s):

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. Your baby should not receive it if he had an allergic reaction to any type of immune globulin, such as medicines given after a kidney transplant or to prevent hepatitis, tetanus, or chickenpox.

How to Use This Medicine:


  • Your baby's doctor will prescribe the exact dose and tell you when it should be given. This medicine is usually given only once after your baby becomes ill with botulism.
  • A nurse or other trained health professional will give this medicine through a needle placed in one of your baby's veins.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Some medicines can affect how this medicine works. Vaccines and other shots may not work as well if your baby receives them during treatment with botulism immune globulin. This effect may last up to 5 months. Talk to your baby's doctor about the best immunization schedule for your baby.

Warnings While Using This Medicine:

  • Tell your baby's doctor if he has diabetes or kidney disease.
  • This medicine is made from human blood products. Blood banks test all donated blood for HIV, hepatitis, and West Nile Virus. The risk that your baby will get a disease from a blood transfusion is rare. Talk to your baby's doctor if you have any concerns about this.
  • Watch your baby closely after he receives this medicine. Some side effects can occur hours or days after he receives the medicine.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Earache, or redness and swelling in the ear
  • Fewer than 8 wet diapers in 1 full day
  • Increased sensitivity to light
  • Neck stiffness, nausea, diarrhea, vomiting
  • Severe drowsiness, fussiness, or crying
  • Trouble breathing or swallowing

If you notice these less serious side effects, talk with your doctor:

  • Chills, fever, or pain
  • Mild skin rash
  • Snoring or noisy breathing

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 5/1/2020

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