Attention deficit hyperactivity disorder (ADHD) is a developmental disorder characterized by inattention, hyperactivity, and impulsivity. It is the most commonly diagnosed behavioral disorder of childhood. Although many people sometimes have difficulty sitting still, paying attention, or controlling impulsive behavior, people with ADHD find that these symptoms greatly interfere with everyday life. Generally, symptoms appear before age 7 and lead to problems in school and in social settings. One- to two-thirds of all children with ADHD continue to have symptoms when they grow up. A diagnosis can be controversial, since there are no lab tests for ADHD, and no objective way to measure a child's behavior. There is no best way to treat ADHD, however, experts agree that taking action early can improve a child's educational and social development.
Signs and Symptoms
A person is diagnosed with ADHD if they have at least 6 symptoms from the following categories, lasting for at least 2 months. In diagnosing children, the symptoms must appear before age 7, and pose a significant challenge to everyday functioning in at least two areas of life (usually home and school). Most children do not show all the symptoms, and they may be different in boys and girls (boys may be more hyperactive and girls more inattentive).
Hyperactivity and Impulsivity
What Causes It?
No one is sure what causes ADHD. Although environmental factors may play a role, researchers are now looking to find answers in the structure of the brain.
Risk factors for ADHD include:
What to Expect at Your Doctor's Office
There is no objective test for ADHD, so making a diagnosis can be difficult. Doctors may use a number of tests and observations. For this reason, it is crucial to make sure the doctor who evaluates you or your child is trained in diagnosing ADHD.
To evaluate a child, the doctor will take a complete medical history and do a thorough exam to check for conditions that may mimic ADHD, such as hyperthyroidism or problems with vision, hearing, and sleeping. Many symptoms show up at home or school rather than the doctor's office, so you may be asked to fill out questionnaires. Your child's teacher may be interviewed. Your doctor will try to determine not only how the child behaves but also where the behavior occurs and how long it lasts. Children with ADHD have long-lasting symptoms that usually show up during stressful situations or situations that require sustained attention (such as school work).
Diagnosing an adult with ADHD can be even more challenging. Because your symptoms would have appeared when you were young, your doctor may try to find out as much as possible about you when you were a child by getting information from your parents or former teachers. (If your symptoms are recent, you are not considered to have adult ADHD.) In addition to ruling out the other conditions mentioned above, your doctor may also check for depression and bipolar disorder, which can mimic ADHD.
Since the cause or causes of ADHD are not known, there is no way to prevent the condition. However, pregnant women can avoid known risk factors, including cigarette smoke and other known toxins. You can manage the condition with medication, behavioral therapy, and lifestyle changes.
How to treat ADHD, particularly in children, is a controversial subject. Current treatment includes therapy or medication, or a combination of both. Studies show that medication by itself, without some kind of therapy, is not likely to improve a child's outcome long term. Family therapy, behavioral therapy, social skills training, and parent skills training are often used. Many parents investigate nutritional therapies (such as elimination diets or high-dose vitamins), however, there is no clear evidence to support these these approaches. Preliminary evidence indicates that homeopathy and mind/body techniques, especially biofeedback, may help improve behavior in children with ADHD.
Parent skills training offered by specialized clinicians provides parents with tools and techniques for managing their child's behavior. Behavior therapy rewards appropriate behavior and discourages destructive behavior. It can be performed by parents and teachers working together with therapists and doctors. For example, older children with ADHD may be rewarded with points or tokens, or even written behavioral contracts with their parents. Creating charts with stars for good behavior may work for younger children. On the other hand, time-outs may discourage undesirable behavior. Other techniques include:
In addition to behavioral intervention at home, changes in the classroom environment (or work, in the case of adolescents or adults) are significant parts of the treatment plan. Hyperactive children do best in highly structured circumstances with a teacher experienced in handling their disruptive behavior and capable of adapting to their distinctive cognitive style. Group interaction can be very challenging for a child with ADHD. Social skills training, appropriate classroom placement, and clear rules of engagement with peers are essential. Preliminary evidence suggests that computer-based attention training in schools is highly effective for students who have ADHD.
Adults with ADHD may benefit from behavioral therapies, including cognitive remediation, couples therapy, and family therapy.
Stimulant medications are the most widely-researched and commonly-prescribed treatments for ADHD. Although researchers do not fully understand how these drugs improve ADHD symptoms, studies indicate they boost the amount of dopamine and serotonin in the brain. Dopamine is a chemical that is associated with activity; and serotonin is a chemical associated with mood and well being. Medications prescribed for ADHD include:
Atomoxetine (Strattera): The first nonstimulant medication approved to treat ADHD. Strattera increases the levels of both dopamine and norepinephrine in the brain. Strattera was first developed as an antidepressant and, as with all antidepressants, carries a "black box" warning that it may increase suicidal thoughts in young children and teenagers.
Antihypertensives (clonidine, guanfacone): These medications are not approved by the Food and Drug Administration (FDA) for the treatment of ADHD, however, they have been used off label for years. Antihypertensives are not as effective as stimulants, however, they are commonly used with stimulants to treat stimulant-induced tics and insomnia.
The most common side effects from these medications are trouble sleeping, decrease in appetite, and nervousness.
Complementary and Alternative Therapies
According to a recent survey, many parents use complementary and alternative treatments (CAM) for their children with ADHD. Nutritional therapies are the most common strategy. Studies show conflicting results, however, if your child appears sensitive to certain foods, talk to your doctor about eliminating them for a brief period to see if symptoms improve. DO NOT put a child on any supplement or CAM diet without the supervision of your doctor.
Developed in the 1970's by Benjamin Feingold, the Feingold diet is based on the idea that artificial colors, flavors, and preservatives, as well as naturally-occurring salicylates (chemicals similar to aspirin that are found in many fruits and vegetables), are a major cause of hyperactive behavior and learning disabilities in children. Studies examining the diet's effects have been mixed. Most show no benefit, although there is some evidence that salicylates may play a role in hyperactivity in a small number of children. Because the Feingold diet is difficult to follow, and also involves changes in family lifestyle (children are encouraged to participate in creating meals, for example), you should talk with your doctor before trying it.
Other dietary therapies may concentrate on eating foods that are high in protein and complex carbohydrates, and eliminating sugar and artificial sweeteners. One study found increased hyperactivity among children after eating foods with artificial food coloring and additives. However, studies show no relation between sugar and ADHD. In one study, children whose diets were high in sugar or artificial sweeteners behaved no differently than children whose diets were free of these substances. This was true even among children whose parents described them as being "sugar sensitive". However, some researchers believe that chronic excessive sugar intake leads to alterations in brain signaling, which would contribute to the symptoms associated with ADHD.
Some doctors who focus on nutrition say they see positive results when testing for food allergies and using an elimination diet. If you think your child might benefit from food allergy testing or an elimination diet, talk to a doctor who has experience in nutrition for children with ADHD.
Vitamins and Minerals
Herbs may help strengthen and tone the body's systems. As with any therapy, you should work with your health care provider before starting treatment. You may use herbs as dried extracts (capsules, powders, or teas), glycerites (glycerine extracts), or tinctures (alcohol extracts). Unless otherwise indicated, make teas with 1 tsp. herb per cup of hot water. Steep covered 5 to 10 minutes for leaf or flowers, and 10 to 20 minutes for roots. Drink 2 to 4 cups per day. You may use tinctures alone or in combination as noted.
Several herbal remedies for ADHD are sold in the United States and Europe, but few scientific studies have investigated whether these herbs improve symptoms of ADHD. One or more of the following calming herbs may be recommended for people with ADHD:
Other herbs commonly contained in botanical remedies for ADHD include:
Relaxation techniques and massage can reduce anxiety and activity levels in children and teens. In one study, teenage boys with ADHD who received a 15-minute massage for 10 consecutive school days showed significant improvement in behavior and concentration compared to those who were guided in progressive muscle relaxation for the same duration of time.
Before prescribing a remedy, homeopaths take into account a person's constitutional type, includes your physical, emotional, and psychological makeup. An experienced homeopath assesses all of these factors when determining the most appropriate treatment for each individual.
In a study of 43 children with ADHD, those who received an individualized homeopathic remedy showed significant improvement in behavior compared to children who received placebo. The homeopathic remedies found to be most effective included:
Mind/body techniques such as hypnotherapy, progressive relaxation, and biofeedback may be useful in treating children and teens. Through these techniques, children are often able to learn coping skills they can use for the rest of their lives. These treatments allow children to gain a sense of control and mastery, increase self esteem, and reduce stress.
Biofeedback operates on the principle that children can be trained to modify brain activity associated with ADHD and increase brain activity associated with attention. Several studies have shown positive results.
Preliminary studies suggest participating in yoga may help reduce symptoms of ADHD.
Prognosis and Complications
As many as half of all children with ADHD who receive appropriate treatment learn to control symptoms and function well as adults. Research suggests that children who receive treatment that combines therapies such as medication, behavioral therapy, and biofeedback are less likely to have behavioral problems as they grow up. Nevertheless, studies show that ADHD persists into adulthood in 60 to 70% of people diagnosed with ADHD in childhood. In most cases, ADHD can be effectively managed throughout life.
American Academy of Pediatrics. Clinical practice guideline: diagnosis and evaluation of the child with attention-deficit/hyperactivity disorder. Pediatrics. 2000;105(5):1158-1170.
Arnold LE, Hurt E, Lofthouse N. Attention-deficit/hyperactivity disorder: dietary and nutritional treatments. Child Adolesc Psychiatr Clin N Am. 2013; 22(3):381-402.
Arnold LE, Pinkham SM, Votolato N. Does zinc moderate essential fatty acid and amphetamine treatment of attention deficit/hyperactivity disorder? J Child Adolesc Psychopharmacol. 2000;10:111-117.
Baumgaertel A. Alternative and controversial treatments for attention-deficit/hyperactivity disorder. Pediatr Clin of North Am. 1999;46(5):977-992.
Bekaroglu M, Aslan Y, Gedik Y. Relationships between serum free fatty acids and zinc, and attention deficit hyperactivity disorder: a research note. J Child Psychol Psychiatry. 1996;37(2):225-227.
Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Boston, Mass: Integrative Medicine Communications; 1998:160, 107.
Bope & Kellerman: Conn's Current Therapy 2013, 1st. ed. St. Louis, MO: Elsevier Saunders; 2012.
Burgess J, Stevens L, Zhang W, Peck L. Long-chain polyunsaturated fatty acids in children with attention-deficit hyperactivity disorder. Am J Clin Nutr. 2000; 71(suppl):327S-330S.
Childress AC, Berry SA. Pharamacotherapy of attention-deficit hyperactivity disorder in adolescents. Drugs. 2012; 72(3):309-325.
Daroff: Bradley's Neurology in Clinical Practice, 6th ed. Philadelphia, PA: Elsevier Saunders; 2012.
Farone S, Mick E. Molecular Genetics of Attention Deficit Hyperactivity Disorder. Psychiatric Clinics of North America. 2010;33(1).
Ferri: Ferri's Clinical Advisor 2015, 1st ed. St. Louis, MO: Elsevier Mosby; 2014.
Ferrin M, Moreno-granados JM, Salcedo-Marin MD, Ruiz-Veguilla M, Perez-Ayala V, Taylor E. Evaluation of a psychoeducation programme for parents of children and adolescents with ADHD: immediate and long-term effects using a blind randomized controlled trial. Eur Child Adolesc Psychiatry. 2014; 23(8):637-47.
Field T, Quintino O, Hernandez-Reif M, Koslovsky G. Adolescents with attention deficit hyperactivity disorder benefit from massage therapy. Adolescence. 1998;33(129):103-108.
Frei H, von Ammon K, Thurneysen A. Treatment of hyperactive children: increased efficiency through modifications of homeopathic diagnostic procedure. Homeopathy. 2006 Jul;95(3):163-370.
Gutgesell H, Atkins D, Barst R, et al. Cardiovascular monitoring of children and adolescents receiving psychotropic drugs: a statement for healthcare professionals from the Committee on Congenital Cardiac Defects, Council on Cardiovascular Disease in the Young, American Heart Association. Circulation. 1999; 99(7):979-982.
Hariprasad VR, Arasappa R, Varambally S, Srinath S, Gangadhar BN. Feasibility and efficacy of yoga as an add-on intervention in attention deficity-hyperactivity disorder: An exploratory study. Indian J Psychiatry. 2013; 55(Suppl 3):S379-84.
Heinrich H, Gevensleben H, Strehl U. Annotation: neurofeedback - train your brain to train behaviour. J Child Psychol Psychiatry. 2007 Jan;48(1):3-16.
Holtmann M, Stadler C. Electroencephalographic biofeedback for the treatment of attention-deficit hyperactivity disorder in childhood and adolescence. Expert Rev Neurother. 2006 Apr;6(4):533-40. Review.
Johnson RJ, Gold MS, Johnson DR, et al. Attention-deficit/hyperactivity disorder: is it time to reappraise the role of sugar consumption? Postgrad Med. 2011; 123(5):39-49.
Kaplan G, Newcorn J. Pharmacotherapy for Child and Adolescent Attention-deficit Hyeractivity Disorder. Pediatric Clinics of North America. Philadelphia, PA: W. B. Saunders Company. 2011;58(1).
Kidd P. Attention deficit / hyperactivity disorder (ADHD) in children: rationale for its integrative management. Altern Med Rev. 2000;5(5):402-428.
Kim BN et al. Phthalates exposure and attention-deficit/hyperactivity disorder in school-age children. Biol Psych. 2009;66(10):958-963.
Kliegman: Nelson Textbook of Pediatrics, 19th ed. Philadelphia, PA: Elsevier Saunders; 2011.
Kozielec T, Starobrat-Hermelin B. Assessment of magnesium levels in children with attention deficit hyperactivity disorder. Magnes Res. 1997;10(2):143-148.
Krummel D, Seligson FH, Guthrie HA. Hyperactivity: is candy causal? Critical Reviews in Food Science and Nutrition. 1996;36(1 and 2):31-47.
Lamont J. Homoeopathic treatment of attention deficit hyperactivity disorder; a controlled study. Br Homoeopath J. 1997;86:196-200.
Lavigne JP, Dulcan MK, LeBailly SA, Binns HJ, Cummins TK, Jha P. Computer-assisted management of attention-deficit/hyperactivity disorder. Pediatrics. 20011; 128(1):e46-53.
Li J, Olsen J, Vestergaard M, Obel C. Low Apgar scores and risk of childhood attention deficit hyperactivity disorder. J Pediatr. 2011; 158(5):775-779.
Linden M, Habib T, Rodojevic V. A controlled study of the effects of EEG biofeedback on cognition and behavior of children with attention deficit disorder and learning disabilities. Biofeedback Self Regul. 1996;21(1):35-49.
Lindstrom K, Lindblad F; Hjern A. Preterm birth and attention-deficit/hyperactivity disorder in schoolchildren. Pediatrics. 2011; 127(5):858-865.
Lubar J, Swartwood MO, Swartwood JN, O'Donnell PH. Evaluation of the effectiveness of EEG neurofeedback training for ADHD in a clinical setting as measured by changes in TOVA scores, behavioral ratings and WISC-R performance. Biofeedback Self Regul. 1995;20(1):83-99.
Lyon MR, Cline JC, Totosy de Zepetnek J, et al. Effect of the herbal extract combination Panax quinquefolium and Ginkgo biloba on attention-deficit hyperactivity disorder: a pilot study. J Psychiatry Neurosci. 2001;26(3):221-228.
Millichap JG, Yee MM. The diet factor in attention-deficit/hyperactivity disorder. Pediatrics. 2012; 129(2):330-337.
Modesto-Lowe V, Yelunina L, Hanjan K. Attention-deficit/hyperactivity disorder: a shift toward resilience? Clin Pediatr (Phil). 2011; 50(6):518-524.
MTA Cooperative Group. A 14-month randomized clinical trial of treatment strategies for attention-deficit/hyperactivity disorder. Arch Gen Psychiatry. 1999;56:1073-1086.
Nigg JT, Nikolas M, Knottnerus M, Cavanaugh K, Friderici K. Confirmation and extension of association of blood lead with attention deficit/hyperactivity disorder (ADHD) and ADHD symptom domains at population-typical exposure levels. J Child Psychol Psychiatry. 2010;51(1):58-65.
Noorbala AA, Akhondzadeh S. Attention-deficit/hyperactivity disorder: etiology and pharmacotherapy. Arch Iran Med. 2006 Oct;9(4):374-380. Review.
Post RE, Kurlansik SL. Diagnosis and management of adult attention-deficit/hyperactivity disorder. Am Fam Physician. 2012; 85(9):890-896.
Rader R, McCauley L, Callen E. Current Strategies in the Diagnosis and Treatment of Childhood Attention Deficit Hyperactivity Disorder. Am Fam Phys. 2009;79(8).
Raishevich N, Jensen P. Attention-deficit hyperactivity disorder. In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF , eds. Nelson Textbook of Pediatrics. 18th ed. Philadelphia, PA: W.B. Saunders Company; 2007:ch. 31.
Rakel: Integrative Medicine, 3rd ed. Philadelphia, PA: Elsevier Saunders; 2012.
Richardson AJ. Omega-3 fatty acids in ADHD and related neurodevelopmental disorders. Int Rev Psychiatry. 2006 Apr;18(2):155-172. Review.
Richardson AJ, Puri BK. The potential role of fatty acids in attention-deficit/hyperactivity disorder. Prostaglandins Leukot Essent Fatty Acids. 2000;63(1/2):79-87.
Starobrat-Hermelin B, Kozielec T. The effects of magnesium physiological supplementation on hyperactivity in children with attention deficit hyperactive disorder (ADHD): positive response to magnesium oral loading test. Magnesium Research. 1997;10(2):149-156.
Steiner NJ, Sheldrick RC, Gotthelf D, Perrin EC. Computer-based attention training in the schools for children with attention deficit/hyperactivity disorder: a preliminary trial. Clin Pediatr (Phil). 2011;50(7):615-622.
Stevens LJ, Zentall SS, Abate ML, Kuczek T, Burgess JR. Omega-3 fatty acids in boys with behavior, learning and health problems. Physiol Behav. 1996;59(4/5):915-920.
Stevens LJ, Zentall SS, Deck JL, et al. Essential fatty acid metabolism in boys with attention-deficit hyperactivity disorder. Am J Clin Nutr. 1995;62:761-768.
Stubberfield TG, Wray JA, Parry TS. Utilization of alternative therapies in attention-deficit hyperactivity disorder. J Paediatr Child Health. 1999;35:450-453.
Sinn N. Nutritional and dietary influences on attention deficit hyperactivity disorder. Nutr Rev. 2008 Oct;66(10):558-68.
Tan G, Schneider S. Attention-deficit hyperactivity disorder: pharmacotherapy and beyond. Postgrad Med. 1997;101(5):201-222.
Thompson L, Thompson M. Neurofeedback combined with training in metacognitive strategies: effectiveness in students with ADD. Appl Psychophysiol Biofeedback. 1998;23(4):243-263.
Toplak ME, Connors L, Shuster J, Knezevic B, Parks S. Review of cognitive, cognitive-behavioral, and neural-based interventions for Attention-Deficit/Hyperactivity Disorder (ADHD). Clin Psychol Rev. 2008 Jun;28(5):801-823. Review.
Toren P, Eldar S, Sela BA, et al. Zinc deficiency in attention-deficit hyperactivity disorder. Biol Psychiatry. 1996; 40:1308-1310.
Uebel-von Sandersleben H, Rothenberger A, Albrecht B, Rothenberger LG, Klement S, Bock N. Ginkgo biloba extract EGb 761 in children with ADHD. Z Kinder Jugendpsychiatr Psychother. 2014; 42(5):337-47.
Van Oudheusden LJ, Scholte HR. Efficacy of carnitine in the treatment of children with attention-deficit hyperactivity disorder. Prostaglandins Leukot Essent Fatty Acids. 2002;76:33-38.
Volkow ND, Wang G, Fowler JS, et al. Therapeutic doses of oral methylphenidate significantly increase extracellular dopamine in the human brain. J Neurosci. 2001;15;21(2):RC121.
Weber W, Newmark S. Complementary and Alternative Medical Therapies for Attention Deficit Hyperactivity Disorder and Autism. Pediatric Clinics of North America. 2007;54(6).
Wender PH, Wolf LE, Wasserstein J. Adults with ADHD. An overview. Ann N Y Acad Sci. 2001;931:1-16.
Wolraich M. Addressing behavior problems among school-aged children: traditional and controversial approaches. Pediatr Rev. 1997;18(8):266-270.
Yorbik O, Ozdag MF, Olgun A, Senol MG, Bek S, Akman S. Potential effects of zinc on information processing in boys with attention deficit hyperactivity disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2008 Apr 1;32(3):662-667.
Review Date: 3/23/2015
Reviewed By: Steven D. Ehrlich, NMD, Solutions Acupuncture, a private practice specializing in complementary and alternative medicine, Phoenix, AZ. Review provided by VeriMed Healthcare Network.
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