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Abobotulinumtoxina (By injection)

AbobotulinumtoxinA (ab-oh-bot-ue-LYE-num-tox-in-ay)

Treats muscle spasms and pain in the neck, arms, wrists, hands, or legs. Also improves the appearance of deep facial lines or wrinkles.

Brand Name(s):


There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. You should not receive it if you had an allergic reaction to abobotulinumtoxinA, other botulinum toxin products, or cow's milk protein, or if you have an infection at the injection area.

How to Use This Medicine:


  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into one of your muscles.
  • A nurse or other health provider will give you this medicine.
  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Some foods and medicines can affect how abobotulinumtoxinA works. Tell your doctor if you are using an allergy or cold medicine, antibiotic medicine, muscle relaxer, or sleep medicine.
  • Tell your doctor if you have received botulinum toxin for any reason in the last 4 months.

Warnings While Using This Medicine:

  • Tell your doctor if you are pregnant or breastfeeding, or if you have trouble swallowing or breathing, or a nerve or muscle disorder, including ALS (Lou Gehrig disease), Lambert-Eaton syndrome, or myasthenia gravis. Tell your doctor if you have had surgery on your face or head.
  • The effects of this medicine may spread from the body area where the injection was given. Symptoms may appear hours to weeks after treatment. Tell your doctor about any new health problems that start or get worse.
  • This medicine may cause muscle weakness or vision problems. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
  • This medicine is made from donated human blood. Some human blood products have transmitted viruses, although the risk is low because donors and donated blood are both tested for viruses. Talk with your doctor about this risk if you are concerned.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Eye pain or irritation, sensitivity of the eyes to sunlight, trouble seeing, blurred or double vision
  • Loss of bladder control
  • Trouble breathing, speaking, or swallowing, neck pain
  • Unusual weakness in other muscles (not where the shot was given)

If you notice these less serious side effects, talk with your doctor:

  • Dry mouth
  • Eyelid drooping or swelling
  • Headache
  • Redness, pain, tenderness, swelling, or weakness where the shot was given
  • Stuffy or runny nose, sore throat
  • Voice changes or losing your voice

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 5/1/2020

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