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Acetohydroxamic acid (By mouth)

Acetohydroxamic Acid (a-seet-oh-hye-drox-AM-ik AS-id)

Used to prevent kidney stones and to help treat a urinary tract infection.

Brand Name(s):


There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. Do not use it if you had an allergic reaction to acetohydroxamic acid, you have kidney disease, or you are pregnant.

How to Use This Medicine:


  • Your doctor will tell you how much medicine to use. Do not use more than directed.
  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
  • It is best to take this medicine on an empty stomach.
  • Missed dose: You must use this medicine on a fixed schedule. Call your doctor or pharmacist if you miss a dose.
  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Do not take iron pills or any supplements that contain iron while you are taking this medicine.
  • Some medicines and foods can affect how acetohydroxamic acid works. Tell your doctor if you are taking diabetes medicine, antibiotics, or vitamin or mineral supplements.
  • Do not drink alcohol while you are using this medicine. Alcohol might cause your skin to become flushed (redness, warmth, and tingling). Call your doctor if the reaction lasts longer than 30 minutes, or if the symptoms are severe.

Warnings While Using This Medicine:

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
  • Tell your doctor if you are breastfeeding, or if you have a history of kidney disease, anemia, or blood clots.
  • This medicine may cause blood clots, especially if you had one before.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Chest pain, shortness of breath
  • Dark urine, decrease in how much or how often you urinate
  • Fast or pounding heartbeat
  • Redness or pain in your leg
  • Unusual bleeding, bruising, or weakness
  • Yellowing of your skin or the whites of your eyes

If you notice these less serious side effects, talk with your doctor:

  • Anxiety, depression, or fatigue
  • Hair loss
  • Nausea, vomiting, or loss of appetite
  • Nervousness or shakiness
  • Warmth, tingling, or redness in your face, neck, arms, or upper chest

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 5/1/2020

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