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Octreotide (By injection)

Octreotide (ok-TREE-oh-tide)

Treats acromegaly (a growth hormone disorder), carcinoid syndrome, or diarrhea caused by tumors in the stomach, bowels, or pancreas.

Brand Name(s):

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. Do not use it if you had an allergic reaction to octreotide.

How to Use This Medicine:

Injectable

  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin or into a vein.
  • A nurse or other health provider will give you this medicine.
  • You may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.
  • You will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas.
  • Use a new needle and syringe each time you inject your medicine.
  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
  • Missed dose: You must use this medicine on a fixed schedule. Call your doctor or pharmacist if you miss a dose.
  • If you store this medicine at home, keep it in the refrigerator. Do not freeze.
    • After first use of the prefilled pen, you can keep it at room temperature, away from heat and direct light, for up to 28 days. Throw away any unused medicine after 28 days.
    • You may also keep the vials at room temperature, away from heat and direct light, for up to 14 days. Throw away any unused medicine after 14 days.
  • Throw away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Some medicines can affect how octreotide works. Tell your doctor if you are using any of the following:
    • Bromocriptine, cyclosporine, quinidine, terfenadine
    • Beta-blocker or calcium channel blocker
    • Diuretic (water pill)
    • Insulin or oral diabetes medicine
    • Medicine for heart rhythm problems
    • Potassium supplements

Warnings While Using This Medicine:

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, gallbladder disease, diabetes, psoriasis, heart or blood vessel problems, vitamin B12 deficiency, thyroid problems, or a history of gallstones.
  • This medicine may cause the following problems:
    • Gallstones, which may lead to swelling of the gallbladder, bile ducts, or pancreas
    • Changes in blood sugar level
    • High blood pressure
  • This medicine may improve fertility in women and may cause unwanted pregnancies. Talk to your doctor if you have concerns.
  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Fast, slow, or uneven heartbeat, trouble breathing
  • Increase in how much or how often you urinate, increased thirst or hunger, weight loss
  • Severe stomach pain, especially spreading to the side or back, severe nausea and vomiting
  • Shaking, trembling, sweating, fast or pounding heartbeat, lightheadedness, confusion
  • Unusual bleeding, bruising, or weakness

If you notice these less serious side effects, talk with your doctor:

  • Headache
  • Pain, burning, or itching where the needle was placed or shot was given

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 5/1/2020

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